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Amfesulfa (amphetamine sulfate) is a central nervous system stimulant used for the treatment of Attention Deficit Hyperactivity Disorder (ADHD) and narcolepsy.
It increases dopamine and norepinephrine levels in the brain to enhance concentration, reduce impulsivity, and promote alertness.
Key Benefits:
Important: Amfesulfa / amphetamine sulfate is a prescription-only Schedule II controlled substance with very high potential for dependence, abuse, and addiction. Use only as prescribed by a specialist.
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Amfesulfa refers to amphetamine sulfate, a potent CNS stimulant. It is indicated for ADHD (in children and adults) and narcolepsy as part of a comprehensive treatment programme that includes psychological, educational, and social interventions.
How Amfesulfa Works Amphetamine sulfate stimulates the release of dopamine and norepinephrine while inhibiting their reuptake. This results in increased alertness, improved attention span, and reduced impulsivity and fatigue.
Main Uses:
Dosage and Administration Dosing is highly individualized and starts low (e.g., 5 mg once or twice daily), titrated gradually. Tablets are taken orally, usually in the morning and early afternoon to avoid insomnia. Treatment requires regular medical review, and the lowest effective dose should be used for the shortest necessary time.
Quality and Formulation Amphetamine sulfate is available as immediate-release tablets (commonly 5 mg or 10 mg). Pharmaceutical-grade products are manufactured under GMP standards. Note: “Amfesulfa” is often used as a street name for amphetamine sulfate in certain regions.
Warnings and Precautions Amphetamine sulfate has a high potential for abuse, addiction, tolerance, and dependence. Serious risks include cardiovascular events (high blood pressure, heart attack, sudden death), psychiatric effects (anxiety, aggression, hallucinations), insomnia, decreased appetite, and growth suppression in children.
Contraindicated in patients with heart disease, hypertension, hyperthyroidism, glaucoma, history of substance abuse, or during/within 14 days of MAO inhibitors. Regular monitoring of blood pressure, heart rate, and growth is essential. Avoid alcohol and other stimulants.
Not recommended during pregnancy or breastfeeding. May impair driving and operating machinery.



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